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Contact Information

Email: Click to Mail

Phone: (805) 893-7532

Fax: (805) 893-4731

Office Location: 3349 Engineering II

Address: Mail Code 5080
Chemical Engineering Dept.
University of California
Santa Barbara,
CA 93106-5080 USA

Lab Phone: (805) 893-5774


Web Pages

Research Group Home Page


Course Pages

ChE 120A Transport Processes



Education & Honors

BS: Chemical Engineering, University of Bombay

MS: Chemical Engineering, Massachusetts Institute of Technology

PhD: Chemical Engineering, Massachusetts Institute of Technology


Honors:
2013 Elected to National Academy of Inventors
2012 Elected Fellow, American Association for the Advancement of Science (AAAS)
2005 Allan P. Colburn Award
2004 CRS-Outstanding Pharmaceutical Research Award
2004 Hendrick C. van Ness Award Lecturer
2004 CRS-Capsugel Innovative Aspects of Oral Delivery Award
2004 Diabetes Technology Peterson Student Award
2003 Global Indus Technovator Award
2003 Editorial Board, Journal of Controlled Release
2003 Editorial Board, Journal of Pharmaceutical Sciences
2003 Chancellor's Award for Excellence in Undergraduate Research
2003 Theme Editor, Advanced Drug Delivery Reviews
2003 Keynote Lecturer, BioTechnica, 2003
2002 Editorial Board, European Journal of Pharmaceutical Science
2001 Outstanding Faculty Award, UCSB
2001 Junior Faculty Research Incentive Award, UCSB
2001 3M Young faculty award
2001 Culpepper Biomedical Pilot Initiative award
2000 Editorial Board, Austral-Asian Journal of Cancer
2000 CRS-Dow Corning Outstanding Research Award
2000 International Research Promotion Council Young Scientist Award
1999 Technology Review Young Innovator Award
1996 Harvard Health Letter Outstanding Research Award
1995 Ebert Prize by the American Pharmaceutical Association
1994-96 Schering-Plough Fellowship
1992 MIT Chemical Engineering Alumni Fellowship
1992 Outstanding Undergraduate Thesis Award
1992 G.P Kane medal and award in Chemical Engineering


Research

My primary research objective is to develop novel methods of drug delivery in order to provide patient-friendly and easy-to-use means of disease management. Development of novel drug delivery methods is contingent upon our ability to control the transport of desired bio-molecules in the tissues against the naturally exerted forces by tissues arising form steric, chemical, and physical interactions of bio-molecules with the tissues. By developing a fundamental understanding of such transport processes, we seek to develop novel strategies involving the use of external forces (ultrasound, chemicals, and high velocity jets) as well as newly fabricated biomaterials with advanced structure-function characteristics for applications in drug delivery.


Publications

Online Publication List


Current Status and Future Prospects of Needle-free Liquid Jet Injectors, Nature Reviews Drug Discovery, in press.

Role of Target Geometry in Phagocytosis, PNAS, 103(13):4930-4, 2006 (cover illustration, commentary in J. Cell Biol., 113(1), 4, 2006.)

Immunization without Needles, Nature Reviews Immunology, 5(12):905-16, 2005.

Dynamics and Spatial Organization of Endosomes in Mammalian Cells, Phys. Rev. Lett., 95(15):158101, 2005.

Design Principles of Chemical Penetration Enhancers for Transdermal Drug Delivery, PNAS, 102(13): 4688-93, 2005.
Commentary in Nature Reviews Drug Discovery, 4:372-73, 2005, JAMA 293:2083, 2005, and Nature
Biotechnology, 23: 437, 2005.

Healing Sound: the Use of Ultrasound in Drug Delivery and Other Therapeutic Applications, Nature Reviews Drug Discovery, 4(3): 255-60, 2005.

Discovery of Safe and Potent Transdermal Penetration Enhancers by High Throughput Screening, Nature Biotechnology 22 (3): 192-197, 2004.
Commentary in Nature Biotechnology 22(3): 165-167 and Nature Reviews Drug Discovery, 22:112-113, 2005,
C& E News, 82(2): 35, 2004.

Current Status and Future Potential of Transdermal Drug Delivery, Nature Reviews Drug Discovery, 3:115-124, 2004.

A Reversibly Switching Surface, Science, 299: 371-774, 2003.
Commentary in Science, 299: 321-323, 2003, C& E News, 81 (3): 6 and 81 (51): 39-50, 2003.

Transdermal Monitoring of Glucose and Other Analytes Using Ultrasound, Nature Medicine, 6:347-350, 2000.

Ultrasound-Mediated Transdermal Protein Delivery, Science, 269: 850-853, 1995.